DEDD2 Antibody, ALEXA FLUOR 555
-
Catalog number
bs-7063R-A555
-
Price
Please ask
-
Size
100ul
-
-
Long name
DEDD2 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
-
Also known as
Anti-DEDD2 PAb ALEXA FLUOR 555
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 555
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
DEDD2
-
Specificity
This is a highly specific antibody against DEDD2.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DEDD2
-
Gene ID Number
162989
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
Apoptotic signals are often triggered by cell surface death receptors through protein-protein interactions mediated by conserved domains such as the death effector domain. A novel death effector domain (DED)-containing protein, DEDD2, has been recently identified. Over-expression of DEDD2 in transfected cells induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas, TRAIL, and FADD. More recently, it has been shown that DEDD2 can bind caspase-8 and -10 in addition to FLIP but not FADD. Like the related protein DEDD, DEDD2 translocates from the cytosol to the nucleus upon induction of apoptosis, and it has been suggested that DEDD2 may target caspase-8 to the nucleus and that DEDD2 thus plays a critical role in death receptor-induced apoptosis. At least two alternatively spliced transcript variants encoding distinct isoforms have been found for DEDD2.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
553nm/568nm
-
Synonyms
Death effector domain containing 2; DED containing protein FLAME 3; DNA binding death effector domain containing protein 2; FADD like anti apoptotic molecule 3; FLAME 3;
-
Properties
For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor, ALEXA FLUOR 555
-
French translation
anticorps
-
Gene target
-
Gene symbol
DEDD2
-
Short name
Anti-DEDD2
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 555
-
Alternative name
DEDD2 Polyclonal Antibody, ALEXA FLUOR 555
-
Alternative technique
antibodies
-
Alternative to gene target
death effector domain containing 2, DEDD2 and IDBG-53904 and ENSG00000160570 and 162989, receptor signaling complex scaffold activity, nuclei, Dedd2 and IDBG-156541 and ENSMUSG00000054499 and 67379, DEDD2 and IDBG-638613 and ENSBTAG00000005761 and 534251
-
Gene info
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
