WYE-354

  • Catalog number
    B1732-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    WYE-354; WYE354; WYE 354; methyl 4-[6-[4-(methoxycarbonylamino)phenyl]-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate
  • Description
    WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2.
  • CAS Number
    1062169-56-5
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₄H₂₉N₇O₅
  • Molecular Weight
    495.53
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent cell-permeable inhibitor of mTOR
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD18074514
  • PubChem CID
    44219749
  • SMILES
    COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5
  • InChi
    InChI=1S/C24H29N7O5/c1-34-23(32)26-17-5-3-16(4-6-17)20-27-21(29-11-13-36-14-12-29)19-15-25-31(22(19)28-20)18-7-9-30(10-8-18)24(33)35-2/h3-6,15,18H,7-14H2,1-2H3,(H,26,32)
  • InChi Key
    IMXHGCRIEAKIBU-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    WYE-354  
  • Short name
    WYE-354
  • Alternative name
    WYE-354
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