WYE-354
-
Catalog numberB1732-5
-
PricePlease ask
-
Size5 mg
-
-
Alternative_nameWYE-354; WYE354; WYE 354; methyl 4-[6-[4-(methoxycarbonylamino)phenyl]-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate
-
DescriptionWYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2.
-
CAS Number1062169-56-5
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₂₄H₂₉N₇O₅
-
Molecular Weight495.53
-
Cell PermeableYes
-
Purity>98%
-
SolubilitiesDMSO
-
HandlingProtect from air and light
-
Tag LineA potent cell-permeable inhibitor of mTOR
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life36 months
-
MDL NumberMFCD18074514
-
PubChem CID44219749
-
SMILESCOC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5
-
InChiInChI=1S/C24H29N7O5/c1-34-23(32)26-17-5-3-16(4-6-17)20-27-21(29-11-13-36-14-12-29)19-15-25-31(22(19)28-20)18-7-9-30(10-8-18)24(33)35-2/h3-6,15,18H,7-14H2,1-2H3,(H,26,32)
-
InChi KeyIMXHGCRIEAKIBU-UHFFFAOYSA-N
-
MSDS AvailableYes
-
Gene target
-
Short nameWYE-354
-
Alternative nameWYE-354
-