BLU9931

• Catalog number
  9639-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-(2-((6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl)amino)-3-methylphenyl)acrylamide
• Description
  BLU9931 is a potent and irreversible small-molecule inhibitor of FGFR4. It potently inhibits FGFR4 activity (IC₅₀ = 3 nM), but only weakly inhibits FGFR1 (IC₅₀ = 591 nM), FGFR2 (IC₅₀ = 493 nM), and FGFR3 (IC₅₀ = 150 nM) activity.
• CAS Number
  1538604-68-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₂₂Cl₂N₄O₃
• Molecular Weight
  509.38
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and irreversible small-molecule inhibitor of FGFR4
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  72710839
• PubChem CID Link
• SMILES
  CC1=C(C(=CC=C1)NC(=O)C=C)NC2=NC=C3C=C(C=CC3=N2)C4=C(C(=CC(=C4Cl)OC)OC)Cl
• InChi
  InChI=1S/C26H22Cl2N4O3/c1-5-21(33)30-18-8-6-7-14(2)25(18)32-26-29-13-16-11-15(9-10-17(16)31-26)22-23(27)19(34-3)12-20(35-4)24(22)28/h5-13H,1H2,2-4H3,(H,30,33)(H,29,31,32)
• InChi Key
  TXEBNKKOLVBTFK-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BLU9931  
• Short name
  BLU9931
• Alternative name
  BLU9931

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