CD45, Recombinant, Human (PTPRC, Protein Tyrosine Phosphatase, Receptor Type C, B220, CD45, CD45R, GP180, LCA, L-CA, Leukocyte Common Antigen, LY5, T200)

• Catalog number
  MBS635951
• Price
  Please ask
• Size
  0,05 mg

• Other size
  please contact us to order other different size
• Description
  Antigens are peptides or recombinant or native dependent on the production method. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CD45   PTPRC   Protein   Tyrosine   Phosphatase   Receptor   B220   CD45   CD45R   GP180   LCA   L-CA   Leukocyte   Common   LY5   T200  
• Gene symbol
  PTPRC, CLTA, PTPRCAP, CPD, GUCY2D, CPT1A, CA2, MUC16, POM121L2, L3MBTL2
• Short name
  CD45, Recombinant, (PTPRC, Protein Tyrosine Phosphatase, Receptor C, B220, CD45, CD45R, GP180, LCA, L-CA, Leukocyte Common Antigen, LY5, T200)
• Technique
  Recombinant, antigen, antigenes, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  CD45, Rec., H. sapiens (protein tyrosine phosphatase, receptor classification, C, Protein Tyrosine Phosphatase, Receptor classification C, B220, CD45, CD45R, GP180, LCA, L-CA, Leukocyte Common protein, LY5, T200)
• Alternative technique
  rec, antigenes
• Alternative to gene target
  protein tyrosine phosphatase, receptor type, C, B220 and CD45 and CD45R and GP180 and L-CA and LCA and LY5 and T200, PTPRC and IDBG-105609 and ENSG00000081237 and 5788, heparan sulfate proteoglycan binding, Cell surfaces, Ptprc and IDBG-195821 and ENSMUSG00000026395 and 19264, PTPRC and IDBG-638670 and ENSBTAG00000023144 and 407152

Gene info

• Identity
  HGNC:9666
• Gene
  PTPRC
• Long gene name
  protein tyrosine phosphatase receptor type C
• Synonyms gene
  • CD45
• Synonyms
  • LCA
  • T200
  • GP180
• GenBank acession
  • Y00062
• Locus
  1q31.3-q32.1
• Discovery year
  1986-01-01
• Entrez gene record
  5788
• Pubmed identfication
  • 2169617
• RefSeq identity
  • NM_002838
• Classification
  • Protein tyrosine phosphatases receptor type
  • Fibronectin type III domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000035702
• Locus Specific Databases
  • PTPRCbase: Mutation registry for CD45 deficiency
  • LRG_95

Gene info

• Identity
  HGNC:2090
• Gene
  CLTA
• Long gene name
  clathrin light chain A
• Synonyms gene name
  • clathrin, light polypeptide (Lca)
  • clathrin, light chain A
• Synonyms
  • Lca
• Locus
  9p13.3
• Discovery year
  1991-08-08
• Entrez gene record
  1211
• Pubmed identfication
  • 7713494
• RefSeq identity
  • NM_007096
• Classification
  • Clathrin subunits
• VEGA ID
  OTTHUMG00000019896

Gene info

• Identity
  HGNC:9667
• Gene
  PTPRCAP
• Long gene name
  protein tyrosine phosphatase receptor type C associated protein
• Synonyms
  • LPAP
  • CD45-AP
• Locus
  11q13.2
• Discovery year
  1996-04-22
• Entrez gene record
  5790
• RefSeq identity
  • NM_005608
• VEGA ID
  OTTHUMG00000150325

Gene info

• Identity
  HGNC:2301
• Gene
  CPD
• Long gene name
  carboxypeptidase D
• Synonyms
  • GP180
• Synonyms name
  • metallocarboxypeptidase D
• GenBank acession
  • U65090
• Locus
  17q11.2
• Discovery year
  1998-04-08
• Entrez gene record
  1362
• Pubmed identfication
  • 9628828
  • 9355738
• RefSeq identity
  • NM_001304
• Classification
  • M14 carboxypeptidases
• VEGA ID
  OTTHUMG00000132797

Gene info

• Identity
  HGNC:4689
• Gene
  GUCY2D
• Long gene name
  guanylate cyclase 2D, retinal
• Synonyms gene
  • CORD6
  • LCA
  • GUC2D
  • GUC1A4
• Synonyms gene name
  • cone rod dystrophy 6
  • guanylate cyclase 2D, membrane (retina-specific)
• Synonyms
  • retGC
  • RETGC-1
  • ROS-GC1
  • CYGD
  • LCA1
• Synonyms name
  • rod outer segment membrane guanylate cyclase
  • retinal guanylate cyclase 1
• GenBank acession
  • L26921
• Locus
  17p13.1
• Discovery year
  1993-11-09
• Entrez gene record
  3000
• Pubmed identfication
  • 1356371
  • 12552567
• RefSeq identity
  • NM_000180
• Classification
  • Guanylate cyclase receptors
• VEGA ID
  OTTHUMG00000108169
• Locus Specific Databases
  • Mutations of the Retinal Guanylate Cyclase Gene and the Retinal Guanylate Cyclase-activating Protein Gene

Gene info

• Identity
  HGNC:2328
• Gene
  CPT1A
• Long gene name
  carnitine palmitoyltransferase 1A
• Synonyms gene
  • CPT1
• Synonyms gene name
  • carnitine palmitoyltransferase 1A (liver)
• Synonyms
  • CPT1-L
  • L-CPT1
• GenBank acession
  • L39211
• Locus
  11q13.3
• Discovery year
  1995-05-30
• Entrez gene record
  1374
• Pubmed identfication
  • 7892212
  • 9070950
• RefSeq identity
  • NM_001876
• VEGA ID
  OTTHUMG00000167892

Gene info

• Identity
  HGNC:1373
• Gene
  CA2
• Long gene name
  carbonic anhydrase 2
• Synonyms gene name
  • carbonic anhydrase II
• Synonyms
  • Car2
  • CA-II
  • CAII
• GenBank acession
  • J03037
• Locus
  8q21.2
• Discovery year
  2001-06-22
• Entrez gene record
  760
• Pubmed identfication
  • 3107918
• RefSeq identity
  • NM_000067
• Classification
  • Carbonic anhydrases
• VEGA ID
  OTTHUMG00000164944

Gene info

• Identity
  HGNC:15582
• Gene
  MUC16
• Long gene name
  mucin 16, cell surface associated
• Synonyms
  • CA125
  • FLJ14303
  • CA-125
• Synonyms name
  • cancer antigen 125
• GenBank acession
  • AF414442
• Locus
  19p13.2
• Discovery year
  2001-07-20
• Entrez gene record
  94025
• Pubmed identfication
  • 11369781
• RefSeq identity
  • NM_024690
• Classification
  • Mucins
• VEGA ID
  OTTHUMG00000169191

Gene info

• Identity
  HGNC:13973
• Gene
  POM121L2
• Long gene name
  POM121 transmembrane nucleoporin like 2
• Synonyms gene name
  • POM121 membrane glycoprotein-like 2 (rat)
  • POM121 membrane glycoprotein-like 2
  • POM121 transmembrane nucleoporin-like 2
• Synonyms
  • POM121-L
• GenBank acession
  • AL021808
• Locus
  6p22.1
• Discovery year
  2001-07-20
• Entrez gene record
  94026
• RefSeq identity
  • NM_033482
• VEGA ID
  OTTHUMG00000014475

Gene info

• Identity
  HGNC:18594
• Gene
  L3MBTL2
• Long gene name
  L3MBTL histone methyl-lysine binding protein 2
• Synonyms gene name
  • l(3)mbt-like 2 (Drosophila)
  • L3MBTL2, polycomb repressive complex 1 subunit
• Synonyms
  • H-l(3)mbt-l
  • DKFZP761I141
  • dJ756G23.3
• GenBank acession
  • AJ305226
• Locus
  22q13.2
• Discovery year
  2002-04-29
• Entrez gene record
  83746
• Pubmed identfication
  • 11682070
  • 21596310
• RefSeq identity
  • NM_031488
• Classification
  • MBT domain containing
• VEGA ID
  OTTHUMG00000150942

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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