AZD8835
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Catalog numberB1661-5
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PricePlease ask
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Size5 mg
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Alternative_nameAZD8835; AZD 8835; AZD-8835; 1-(4-(5-(5-amino-6-(5-(tert-butyl)-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1H-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one
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DescriptionAZD8835 is a potent and selective inhibitor of PI3Kδ and PI3Kα with IC50 of 5.7 nM and 6.2 nM, with selectivity against PI3Kβ (IC50 431 nM) and PI3Kγ (IC50 90 nM).
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CAS Number1620576-64-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₂H₃₁N₉O₃
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Molecular Weight469.55
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA dual PI3Kα and PI3Kδ inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID76685059
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SMILESCCN1C(=NC(=N1)C2CCN(CC2)C(=O)CCO)C3=CN=C(C(=N3)C4=NN=C(O4)C(C)(C)C)N
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InChiInChI=1S/C22H31N9O3/c1-5-31-19(26-18(29-31)13-6-9-30(10-7-13)15(33)8-11-32)14-12-24-17(23)16(25-14)20-27-28-21(34-20)22(2,3)4/h12-13,32H,5-11H2,1-4H3,(H2,23,24)
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InChi KeyZGRDYKFVDCFJCZ-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameAZD8835
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Alternative nameAZD8835
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