AZD8835

  • Catalog number
    B1661-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    AZD8835; AZD 8835; AZD-8835; 1-(4-(5-(5-amino-6-(5-(tert-butyl)-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1H-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one
  • Description
    AZD8835 is a potent and selective inhibitor of PI3Kδ and PI3Kα with IC50 of 5.7 nM and 6.2 nM, with selectivity against PI3Kβ (IC50 431 nM) and PI3Kγ (IC50 90 nM).
  • CAS Number
    1620576-64-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₂H₃₁N₉O₃
  • Molecular Weight
    469.55
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A dual PI3Kα and PI3Kδ inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    76685059
  • SMILES
    CCN1C(=NC(=N1)C2CCN(CC2)C(=O)CCO)C3=CN=C(C(=N3)C4=NN=C(O4)C(C)(C)C)N
  • InChi
    InChI=1S/C22H31N9O3/c1-5-31-19(26-18(29-31)13-6-9-30(10-7-13)15(33)8-11-32)14-12-24-17(23)16(25-14)20-27-28-21(34-20)22(2,3)4/h12-13,32H,5-11H2,1-4H3,(H2,23,24)
  • InChi Key
    ZGRDYKFVDCFJCZ-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    AZD8835  
  • Short name
    AZD8835
  • Alternative name
    AZD8835
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