anti- NOXA2/p67phox antibody

• Catalog number
  FNab05808
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Immunogen
  neutrophil cytosolic factor 2
• Synonyms
  FLJ93058, NADPH oxidase activator 2, NCF 2, NCF2, Neutrophil cytosol factor 2, neutrophil cytosolic factor 2, NOXA2, P67 PHOX, p67phox
• Calculated MW
  68 kDa
• Uniprot ID
  P19878
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC, IF
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab05808( NCF2 Antibody) at dilution of 1:50
• Image4
  COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab05808(NCF2 antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NOXA2/p67phox  
• Gene symbol
  NCF2
• Short name
  anti- NOXA2/p67phox antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- NOXA2/p67phox (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7661
• Gene
  NCF2
• Long gene name
  neutrophil cytosolic factor 2
• Synonyms gene name
  • neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)
• Synonyms
  • p67phox
  • NOXA2
• Synonyms name
  • NADPH oxidase activator 2
  • chronic granulomatous disease, autosomal 2
• GenBank acession
  • BC001606
• Locus
  1q25.3
• Discovery year
  1989-05-25
• Entrez gene record
  4688
• RefSeq identity
  • NM_000433
• Classification
  • Tetratricopeptide repeat domain containing
• VEGA ID
  OTTHUMG00000035329
• Locus Specific Databases
  • NCF2base: Mutation registry for autosomal recessive chronic granulomatous disease (CGD), deficiency of p67phox
  • LRG_88

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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