Carcinoembryonic Antigen (CEA)/ CD66

• Catalog number
  GEN438079
• Price
  Please ask
• Size
  100ug

• Also known as
  Carcinoembryonic Antigen
• Other names
  carcinoembryonic antigen-related cell adhesion molecule 5 preproprotein; Carcinoembryonic antigen-related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; meconium antigen 100; carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD_antigen: CD66e
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CEACAM5
• Gene name synonims
  N/A
• Other gene names
  CEACAM5; CEACAM5; CEA; CD66e; CEA; CEA
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a (COL-1) + IgG1 (CEA31 & C66/261)
• Clone
  COL-1 + CEA31 + C66/261
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology (IH)
• Description
  Antigens are peptides or recombinant or native dependent on the production method.

• Gene target
  Carcinoembryonic   CEA   CD66  
• Gene symbol
  CEACAM7, CEACAM5, PSG2
• Short name
  Carcinoembryonic Antigen (CEA)/ CD66
• Technique
  antigen, antigenes
• Alternative name
  Anti-Carcinoembryonic Antigen (CEA)/ CD66
• Alternative technique
  antigenes

Gene info

• Identity
  HGNC:1819
• Gene
  CEACAM7
• Long gene name
  CEA cell adhesion molecule 7
• Synonyms gene
  • CGM2
• Synonyms gene name
  • carcinoembryonic antigen-related cell adhesion molecule 7
  • carcinoembryonic antigen related cell adhesion molecule 7
• Synonyms
  • CEA
• Synonyms name
  • carcinoembryonic antigen gene family member 2
• GenBank acession
  • X98311
• Locus
  19q13.2
• Discovery year
  1991-09-12
• Entrez gene record
  1087
• Pubmed identfication
  • 7806520
  • 9135022
• RefSeq identity
  • NM_006890
• Classification
  • V-set domain containing
  • CEA cell adhesion molecule family
• VEGA ID
  OTTHUMG00000151063

Gene info

• Identity
  HGNC:1817
• Gene
  CEACAM5
• Long gene name
  CEA cell adhesion molecule 5
• Synonyms gene
  • CEA
• Synonyms gene name
  • carcinoembryonic antigen-related cell adhesion molecule 5
  • carcinoembryonic antigen related cell adhesion molecule 5
• Synonyms
  • CD66e
• GenBank acession
  • M17303
• Locus
  19q13.2
• Discovery year
  1986-01-01
• Entrez gene record
  1048
• RefSeq identity
  • NM_004363
• Classification
  • I-set domain containing
  • V-set domain containing
  • CEA cell adhesion molecule family
  • CD molecules
• VEGA ID
  OTTHUMG00000151061

Gene info

• Identity
  HGNC:9519
• Gene
  PSG2
• Long gene name
  pregnancy specific beta-1-glycoprotein 2
• Synonyms gene
  • PSBG2
• Synonyms
  • PSGGB
  • PSG1
  • CEA
• Synonyms name
  • pregnancy-specific beta-1 glycoprotein
  • pregnancy-specific beta-1-glycoprotein 7
  • carcinoembryonic antigen SG8
• Locus
  19q13.31
• Discovery year
  1991-06-06
• Entrez gene record
  5670
• Pubmed identfication
  • 2377620
• RefSeq identity
  • NM_031246
• Classification
  • Pregnancy specific glycoproteins
  • V-set domain containing
• VEGA ID
  OTTHUMG00000151547

MeSH Data

• Name
  Embryo Research
• Concept
  Scope note: Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus during the prenatal stage of development that is characterized by rapid morphological changes and the differentiation of basic structures. In humans, this includes the period from the time of fertilization to the end of the eighth week after fertilization.
• Tree numbers
  • E05.313
• Qualifiers
  economics, ethics, history, legislation & jurisprudence

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