Description
An irreversible inhibitor of serine proteases (such as thrombin, trypsin and chymotrypsin) and mammalian acetylcholinesterase. It causes sulfonylation of the active-site serine residues. Inhibits cysteine proteases like papain (reversible by DTT treatment). Also inhibits internucleosomal DNA fragmentation in immature thymocytes.
Peptide sequence
N/A
CAS number
329-98-6
Molecular weight
174.2
Category
Biochemicals
Other name
α-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, Phenylmethylsulfonyl fluoride
Molecular formula
C₇H₇FO₂S
Physical appearance
White solid
Supplied with
N/A
Is this a salt?
No
Is it cell-permeable?
No
Purification
≥99%
Reconstitute instructions
EtOH (10%)
Storage condition
-20°C
Shipping condition
RT
Maximum time for storage
24months
Storage instructions
Protect from moisture
Additional description
For cells, cell lines and tissues in culture till half confluency.
Gene targetPMSF
for
activation
Short name
PMSF for activation
Technique
activation
Alternative name
PMSF to measure cellular activation
Tissue
cell
