FIN56

• Catalog number
  B2308-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N2,N7-Dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide
• Description
  FIN56 is a specific inducer of ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS). FIN56 activates squalene synthase (SQS) leading to coenzyme Q10 depletion. Also induces degradation of glutathione peroxidase 4 (GPX4), via acetyl-CoA carboxylase (ACC).
• CAS Number
  1083162-61-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₅H₃₁N₃O₅S₂
• Molecular Weight
  517.66
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (>40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A ferroptosis inducer
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  118986699
• PubChem CID Link
• SMILES
  C1CCC(CC1)NS(=O)(=O)C2=CC3=C(C=C2)C4=C(C3=NO)C=C(C=C4)S(=O)(=O)NC5CCCCC5
• InChi
  InChI=1S/C25H31N3O5S2/c29-26-25-23-15-19(34(30,31)27-17-7-3-1-4-8-17)11-13-21(23)22-14-12-20(16-24(22)25)35(32,33)28-18-9-5-2-6-10-18/h11-18,27-29H,1-10H2
• InChi Key
  JLCFMMIWBSZOIS-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  YES

• Gene target
  FIN56  
• Short name
  FIN56
• Alternative name
  FIN56

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