FIN56
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Catalog numberB2308-5
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PricePlease ask
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Size5 mg
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Alternative_nameN2,N7-Dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide
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DescriptionFIN56 is a specific inducer of ferroptosis, a non-apoptotic form of cell death characterized by iron-dependent accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS). FIN56 activates squalene synthase (SQS) leading to coenzyme Q10 depletion. Also induces degradation of glutathione peroxidase 4 (GPX4), via acetyl-CoA carboxylase (ACC).
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CAS Number1083162-61-1
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₅H₃₁N₃O₅S₂
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Molecular Weight517.66
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Cell PermeableYes
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Purity≥98%
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SolubilitiesDMSO (>40 mg/ml)
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HandlingProtect from air and light
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Tag LineA ferroptosis inducer
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID118986699
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SMILESC1CCC(CC1)NS(=O)(=O)C2=CC3=C(C=C2)C4=C(C3=NO)C=C(C=C4)S(=O)(=O)NC5CCCCC5
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InChiInChI=1S/C25H31N3O5S2/c29-26-25-23-15-19(34(30,31)27-17-7-3-1-4-8-17)11-13-21(23)22-14-12-20(16-24(22)25)35(32,33)28-18-9-5-2-6-10-18/h11-18,27-29H,1-10H2
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InChi KeyJLCFMMIWBSZOIS-UHFFFAOYSA-N
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MSDS AvailableYES
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Gene target
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Short nameFIN56
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Alternative nameFIN56
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