Anti-ACTH Antibody (r57)

• Catalog number
  A1419-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  ACTH
• Target Alternative Name
  Adrenocorticotropin, alpha or beta or gamma Melanocyte Stimulating Hormone (MSH) or Melanotropin, beta-Endorphin, beta or gamma Lipotropin (LPH), CLIP, Met Enkephalin, POC, POMC
• Antibody Type
  Monoclonal
• Species Reactivities
  Human, Mouse and Rat
• Immunogen Sequence
  N-terminal fragment of human ACTH conjugated to KLH
• Accession
  P01189
• Gene Id
  5443
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 10 mM PBS with 0.05% BSA & 0.05% azide
• Purification
  Protein A/G purification
• Application
  ELISA, FC, ICC/IF, IHC
• Positive Control
  IHC: human pituitary gland
• Application And Usages
  ELISA, FC: 0.5-1 ug/1X106 cells, IF: 0.5-1 ug/ml, IHC (Formalin-fixed): 0.5-1 ug/ml
• Description
  ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to CLIP (aa 25-39 of ACTH); does not react with Synacthen (aa1-24 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Not Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  Adrenocorticotropic hormone (ACTH), or corticotrophins. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ACTH   r57  
• Gene symbol
  POMC
• Short name
  Anti-ACTH Antibody (r57)
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG1
• Alternative name
  Antibody toACTH (antibody to-) (r57)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9201
• Gene
  POMC
• Long gene name
  proopiomelanocortin
• Synonyms
  • MSH
  • POC
  • CLIP
  • ACTH
  • NPP
  • LPH
• Synonyms name
  • adrenocorticotropin
  • beta-lipotropin
  • alpha-melanocyte stimulating hormone
  • beta-melanocyte stimulating hormone
  • beta-endorphin
  • adrenocorticotropic hormone
  • opiomelanocortin prepropeptide
• Locus
  2p23.3
• Discovery year
  1986-01-01
• Entrez gene record
  5443
• Pubmed identfication
  • 6254047
  • 9620771
• RefSeq identity
  • NM_001035256
• Classification
  • Neuropeptides
• VEGA ID
  OTTHUMG00000094764

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products