Clioquinol

  • Catalog number
    2454-1G
  • Price
    Please ask
  • Size
    1 g
  • Alternative_name
    5-Chloro-8-hydroxy-7-iodoquinoline, 5-chloro-7-iodo-8-quinolinol; CQ
  • Description
    An antiparasitic agent that forms stable complexes with copper and used for treatment of Alzheimer’s disease. Displays anticancer properties by inhibition of proteasome activity. It targets tumor proteasome in vivo in a copper-dependent manner, resulting in formation of an active AR (androgen receptor) inhibitor and apoptosis inducer that is responsible for its observed antiprostate tumor effect.
  • CAS Number
    130-26-7
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₉H₅CIlNO
  • Molecular Weight
    305.5
  • Cell Permeable
    Yes
  • Purity
    ≥95% by HPLC
  • Solubilities
    DMSO (>25 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A proteasome inhibitor and an anticancer agent
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD00006787
  • PubChem CID
    2788
  • SMILES
    C1=CC2=C(C(=C(C=C2Cl)I)O)N=C1
  • InChi
    InChI=1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
  • InChi Key
    QCDFBFJGMNKBDO-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Clioquinol
  • Alternative name
    Clioquinol
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