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Mouse Anti Mouse ASIC1 Monoclonal IgG1 Clone S271 44

Mouse Anti Mouse ASIC1 Monoclonal IgG1 Clone S271 44 is available 19 times from Stressmark antibodies labs

SMC-427S | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 12 µg | 55.57 USD

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SMC-427D-A565 | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 440.07 USD

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SMC-427D-BI | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 435.63 USD

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SMC-427D-P594 | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 447.85 USD

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SMC-427D | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 386.73 USD

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SMC-427D-HRP | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 426.74 USD

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SMC-427D-ALP | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 433.41 USD

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SMC-427D-A594 | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 440.07 USD

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SMC-427D-A700 | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 440.07 USD

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SMC-427D-FITC | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 431.18 USD

Catalog number SMC-427D-FITC
Price 431.18 USD
Size 100 µg
Antibody's full description Mouse Anti-Mouse ASIC1 Monoclonal IgG1 Antibody, Clone: S271-44: FITC
Net weight (g) 0.1
1. Gene info
Identity5700
Synonyms gene name
  • immunoglobulin heavy variable (III)-44
  • immunoglobulin heavy variable (III)-44 pseudogene
Synonyms
GenBank acession
Discovery year2000-04-17
RefSeq identity
Havana BLAST/BLATOTTHUMG00000152065
2. Gene info
Identity100
GeneASIC1
Synonyms gene
Synonyms gene name
  • amiloride-sensitive cation channel 2, neuronal
  • acid-sensing (proton-gated) ion channel 1
  • acid sensing (proton gated) ion channel 1
Synonyms
GenBank acession
Discovery year1997-09-05
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000169812
MeSH Data
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Product images
    #Mouse#.jpg

SMC-427D-A488 | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 440.07 USD

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SMC-427D-A655 | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 440.07 USD

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SMC-427D-A633 | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 440.07 USD

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SMC-427D-APC | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 438.96 USD

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SMC-427D-A680 | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 440.07 USD

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SMC-427D-STR | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 437.85 USD

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SMC-427D-PCP | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 438.96 USD

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SMC-427D-RPE | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 436.74 USD

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SMC-427D-A390 | Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44 size: 100 µg | 441.19 USD

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Clone S271-44
Immunogen Fusion protein amino acids 460-526 (Cytoplasmic C-terminus) of mouse ASIC1
Antibody's category Monoclonal Antibodies
Antibody's other name ACCN2 Antibody, Acid-sensing (proton-gated) ion channel Antibody, Acid-sensing ion channel 1 Antibody, Amiloride-sensitive cation channel 2 neuronal Antibody, BNAC2 Antibody, Brain sodium channel 2 Antibody
Raised in Mouse
Antibody's target ASIC1
Primary research fields Neuroscience, Ion Channels, Sodium Channels, Proton-Gated Sodium Channels
Brandname None
Antibodies' applications WB, IHC, ICC/IF
Antibody's reactivity Mouse, Rat
Antibody's dilutions WB (1:1000); optimal dilutions for assays should be determined by the user.
Purity Protein G Purified
Antibody buffer for storage PBS pH7.4, 50% glycerol, 0.09% sodium azide
Antibody's concentration 1 mg/ml
Antibody's specificity Detects ~60kDa.
Storage recommendations -20ºC
Shipping recommendations Blue Ice or 4ºC
Antibody certificate of analysis 1 µg/ml of SMC-427 was sufficient for detection of ASIC1 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Antibody in cell Cell Membrane
Tissue specificity See included datasheet or contact our support service
Scientific context Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. Insitu hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety.
Bibliography 1. Garcia-Anoveros J., Derfler B., Neville-Golden J., Hyman B.T. and Corey D.P. (1997) Proc. Natl. Acad. Sci. USA 94: 1459-1464. 2. Waldmann R., Champigny G., Bassilana F., Heurteaux C. and Lazdunski M. (1997) Nature. 386: 173-177. 3. Grunder S., Geisler H.S., Rainier S. and Fink J.K. (2001) Eur. J. Hum. Genet. 9:672-676. 4. Chen C.C., Zimmer A., Sun W.H., Hall J., Brownstein M.J. and Zimmer A. (2002) Proc. Natl. Acad. Sci. USA 99: 8992-8997. 5. Wemmie J.A., et al. (2004) Proc. Natl. Acad. Sci. USA 101: 3621-3626 .
Released date 15-Feb-2013
Tested applications To be tested
Tested reactivity To be tested
NCBI number NP_033727.1
Gene number 11419
Protein number Q6NXK8
Antibody's datasheet Contact our support service
Representative figure linkmore | details
Representative figure legend Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-ASIC1 Monoclonal Antibody, Clone S271-44 (SMC-427). Tissue: Neuroblastoma cell line SK-N-BE. Species: Human. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: Mouse Anti-ASIC1 Monoclonal Antibody (SMC-427) at 1:100 for 60 min at RT. Secondary Antibody: Goat Anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain at 1:1000, 1:5000 for 60min RT, 5min RT. Localization: Cell Membrane, Nucleus. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) ASIC1 Antibody (D) Composite. Western Blot analysis of Rat brain lysates showing detection of ASIC1 protein using Mouse Anti-ASIC1 Monoclonal Antibody, Clone S271-44 (SMC-427). Primary Antibody: Mouse Anti-ASIC1 Monoclonal Antibody (SMC-427) at 1:100, 1:250, 1:500, and 1:1000. Mouse Anti-ASIC1 Antibody [S271-44] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Neuroblastoma cell line SK-N-BE (SMC-427) Mouse Anti-ASIC1 Antibody [S271-44] used in Western Blot (WB) on Rat brain lysates (SMC-427)
Warning information Non-hazardous
Country of production Canada
Total weight (kg) 1.4
Stock availability In Stock
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
About Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
Test Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name Mus musculus
Gene targetASIC1 Monoclonal IgG1 S271-44
Short name Mouse Anti-Mouse ASIC1 Monoclonal IgG1, Clone S271-44
Technique Mouse, anti
Host mouse
Isotype IgG1
Species Mouse
Alternative name Mouse antibody to-Mouse ASIC1 monoclonal IgG1, clonality S271-44
Alternative technique antibodies
Clone name S271-44
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+32-(0)1-658-90-45 [email protected]
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  • IgG1
  • S271-44
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