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2 5 Dideoxyadenosine

2 5 Dideoxyadenosine is available 4 times from Biovision labs

2770-5 | 2',5'-Dideoxyadenosine size: 5 mg | 374.73 USD

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2770-25 | 2',5'-Dideoxyadenosine size: 25 mg | 922.4 USD

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2770-25 | 2',5'-Dideoxyadenosine for cell activation size: 25 mg | 872.82 USD

Additional description For cells, cell lines and tissues in culture till half confluency.
Short name 2',5'-Dideoxyadenosine for activation
Alternative name 2',5'-Dideoxyadenosine to measure cellular activation
MeSH Data
Concept
Registry number:4Q86AH641A
Scope note:A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is an inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal side effect is nephrotoxicity. In vivo, dideoxyadenosine is rapidly metabolized to DIDANOSINE (ddI) by enzymatic deamination; ddI is then converted to dideoxyinosine monophosphate and ultimately to dideoxyadenosine triphosphate, the putative active metabolite.
CASN1 number:Adenosine, 2',3'-dideoxy-
Tree numbers
  • D03.633.100.759.590.138.325.105
  • D13.570.230.229.105
  • D13.570.230.500.105
  • D13.570.583.138.325.105
Additional information
Product images
    #0#.jpeg2',5'-Dideoxyadenosine

2770-5 | 2',5'-Dideoxyadenosine for cell activation size: 5 mg | 276.72 USD

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Alternate Name/Synonyms 2',5'-Dideoxy-D-adenosine; 2’,5’-DDA
Appearance White to off-white solid
Formulation N/A
CAS Number 6698-26-6
Peptide sequence N/A
Molecular Formula C₁₀H₁₃N₅O₂
Molecular Weight 235.25
Purity ≥98% by HPLC
Solubility/Reconstitution Instructions H₂O (~20 mg/ml, warming) or DMSO (~ 30 mg/ml)
Handling Protect from light and moisture
Tagline An adenylate cyclase inhibitor
Storage Temp. -20°C
Shipping Conditions Gel Pack
Shelf Life 36 months
MDL Number MFCD00210904
PubChem CID 65166
Category Biochemicals
Description 2’, 5’- Dideoxyadenosine is a cell-permeable inhibitor of adenylate cyclase (IC₅₀ = 2.7 µM). Inhibits growth and causes cell differentiation (1.5 µM) in K562 cells.
CAS number 6698-26-6
Molecular weight 235.25
Other name 2',5'-Dideoxy-D-adenosine; 2’,5’-DDA
Molecular formula C₁₀H₁₃N₅O₂
Physical appearance White to off-white solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Y
Purification ≥98% by HPLC
Reconstitute instructions H₂O (~20 mg/ml, warming) or DMSO (~ 30 mg/ml)
Storage condition -20°C
Shipping condition Gel Pack
Maximum time for storage 36 months
Storage instructions Protect from light and moisture
Technique activation
Tissue cell
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