Rabbit Anti Human TFRC Antibody-Biotin

• Catalog number
  CSB-PA07219D0Rb_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Human TFRC, Biotin
• Synonym name
  TFRC Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA
• Conjugation
  Biotin
• Antibody isotype
  IgG
• UniProt ID
  P02786
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant human Transferrin receptor protein 1 protein (94-754AA)
• Immunogen species
  Human
• Alias
  T9,p90,CD71,TFRC
• Background
  Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
• Clonality
  Polyclonal antibody
• Shipping and storage
  TFRC Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional conjugation
  Biotinylated
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  TFRC  
• Gene symbol
  TFRC
• Short name
  Anti-TFRC
• Technique
  anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
• Host
  Rabbit, Rabbits
• Label
  Biotin
• Species
  Human, Humans
• Alternative name
  TFRC Antibody,Biotin conjugated
• Alternative technique
  antibodies, rabbit-anti
• Alternative to gene target
  transferrin receptor (p90, CD71), CD71 and p90 and T9 and TFR and TFR1 and TR and TRFR, TFRC and IDBG-71016 and ENSG00000072274 and 102724492,7037, poly(A) RNA binding, Extracellular, Tfrc and IDBG-154429 and ENSMUSG00000022797 and 22042, TFRC and IDBG-633841 and ENSBTAG00000032719 and 100852305,504698

Gene info

• Identity
  HGNC:11763
• Gene
  TFRC
• Long gene name
  transferrin receptor
• Synonyms gene name
  • transferrin receptor (p90, CD71)
• Synonyms
  • CD71
  • TFR1
  • p90
• GenBank acession
  • X01060
• Locus
  3q29
• Discovery year
  2001-06-22
• Entrez gene record
  7037
• Classification
  • M28 metallopeptidases
  • CD molecules
• VEGA ID
  OTTHUMG00000155714

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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