LIGHT Antibody
-
Catalog number5607-100
-
PricePlease ask
-
Size100 µg
-
-
Antibody TargetLIGHT
-
Target Alternative NameTumor necrosis factor ligand, TNF14, TNF 14, TNF-14
-
Antibody TypePolyclonal
-
Species ReactivitiesHuman
-
Immunogen SequenceRecombinant human LIGHT
-
AccessionAAC39563
-
Gene Id8740
-
AppearanceColorless liquid
-
FormLiquid
-
Concentration0.5 mg/ml
-
Formulation100 µg (0.5 mg/ml) antigen affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
-
PurificationAffinity purified
-
ApplicationWestern blot
-
Application And UsagesWestern blotting (0.5-1 µg/ml). However, the optimal conditions should be determined individually. The antibody detects human LIGHT. Reactivity to other species has not been tested.
-
DescriptionLIGHT is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors; the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3).
-
Storage Condition-20 °C
-
Shipping Conditiongel pack
-
Shelf Life12 months
-
UsageFor Research Use Only! Not to be used in humans.
-
HandlingThe antibody solution should be gently mixed before use.
-
Western Blot VerifiedVerified
-
Immunocytochemistry VerifiedNot Verified
-
Immunofluorescence VerifiedNot Verified
-
Immunoprecipitation VerifiedNot Verified
-
FACS VerifiedNot Verified
-
ELISA VerifiedNot Verified
-
ChIP VerifiedNot Verified
-
Flow Cytometry VerifiedNot Verified
-
PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolTNFSF14
-
Short nameLIGHT Antibody
-
TechniqueAntibody, light, antibodies against human proteins, antibodies for
-
IsotypeRabbit IgG
-
Alternative nameLIGHT (antibody to-)
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameTNF superfamily member 14
-
Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 14
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1998-12-04
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Tumor necrosis factor superfamily
- CD molecules
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data