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anti-ATM Antibody

  • Catalog number
    3813-100
  • Product name
    anti-ATM Antibody
  • Size
    ATM Antibody
  • Price
    338EUR
  • Supplier
    biovision antibodies-kits-proteins
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human, mouse
  • Purification method:
    Affinity purified
  • Immunogene sequence:
    Synthetic peptide from human Ataxia Telangiectasia Mutated (ATM)
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Form of antibody:
    Liquid
  • This antibody has been succesfully tested for use in following methods:
    Western blot, Immunoprecipitation
  • Target of this antibody:
    ATM
  • Formulation of this antibody:
    100 µl affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal
  • Alternative names of antibody target:
    AT complementation group A, AT complementation group C, AT complementation group D, AT complementation group E , ATE, ATDC
  • Recommended usage:
    Western blotting (1:500-2000) and immunoprecipitation. However, the optimal concentrations should be determined individually. Human L-40 cell lysate can be used as a positive control for Western blotting. The antibody recognizes ATM in samples from human and mouse origins. Reactivity to other species has not been tested.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Background information:
    The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy termini that is not present in the PI 3- and PI 4-kinases. All of the members of the PIK-related kinases are also larger than 270 kDa. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT), which is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiectases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and they display delays in p53 induction.
  • Concentration of antibody:
    0.5 mg/ml
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by biovision antibodies-kits-proteins they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Gene target
  • Short name
    anti-ATM Antibody
  • Technique
    Antibody, antibody to, antibodies against human proteins, antibodies for
  • Alternative name
    antibody to-ataxia telangiectasia mutated (Antibody to)
  • Alternative technique
    antibodies
  • Alternative to gene target
    ataxia telangiectasia mutated, AT1 and ATA and ATC and ATD and ATDC and ATE and TEL1 and TELO1, ATM and IDBG-70193 and ENSG00000149311 and 472, this GO :0000077 and DNA damage checkpoint and biological process this GO :0000723 and telomere maintenance and biological process this GO :0000724 and double-strand break repair via homolo this GO us recombination and biological process this GO :0000781 and chromosome, telomeric region and cellular component this GO :0001666 and response to hypoxia and biological process this GO :0001756 and somitogenesis and biological process this GO :0002331 and pre-B cell allelic exclusion and biological process this GO :0003677 and DNA binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004677 and DNA-dependent protein kinase activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006975 and DNA damage induced protein phosphorylation and biological process this GO :0006977 and DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007094 and mitotic spindle assembly checkpoint and biological process this GO :0007131 and reciprocal meiotic recombination and biological process this GO :0007165 and signal transduction and biological process this GO :0007292 and female gamete generation and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016303 and 1-phosphatidylinositol-3-kinase activity and molecular function this GO :0016572 and histone phosphorylation and biological process this GO :0016772 and transferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, alcohol group as acceptor and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0030889 and negative regulation of B cell proliferation and biological process this GO :0032403 and protein complex binding and molecular function this GO :0035174 and histone serine kinase activity and molecular function this GO :0035404 and histone-serine phosphorylation and biological process this GO :0036092 and phosphatidylinositol-3-phosphate biosynthetic process and biological process this GO :0042159 and lipoprotein catabolic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043517 and positive regulation of DNA damage response, signal transduction by p53 class mediator and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0047485 and protein N-terminus binding and molecular function this GO :0048599 and oocyte development and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0071044 and histone mRNA catabolic process and biological process this GO :0071480 and cellular response to gamma radiation and biological process this GO :0072434 and signal transduction involved in mitotic G2 DNA damage checkpoint and biological process this GO :0090399 and replicative senescence and biological process, transferase activity, this GO :0003677: DNA binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004677: DNA-dependent protein kinase activity and also this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016303: 1-phosphatidylinositol-3-kinase activity and also this GO :0016772: transferase activity, transferring phosphorus-containing groups and also this GO :0016773: phosphotransferase activity, alcohol group as acceptor and also this GO :0032403: protein complex binding and also this GO :0035174: histone serine kinase activity and also this GO :0046983: protein dimerization activity and also this GO :0047485: protein N-terminus binding, this GO :0003677: DNA binding, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004677: DNA-dependent protein kinase activity, this GO :0005488: binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016303: 1-phosphatidylinositol-3-kinase activity, this GO :0016772: transferase activity, transferring phosphorus-containing groups, this GO :0016773: phosphotransferase activity, alcohol group as acceptor, this GO :0032403: protein complex binding, this GO :0035174: histone serine kinase activity, this GO :0046983: protein dimerization activity, this GO :0047485: protein N-terminus binding, nuclei, Atm and IDBG-165511 and ENSMUSG00000034218 and 11920, ATM and IDBG-629882 and ENSBTAG00000003111 and 526824
1. Gene info
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