Human BRCA 1/2 Gene Mutation Detection Kit. (High-Throughput sequencing)

  • Catalog number
    SpaceGen-003
  • Price
    Please ask
  • Size
    1 Kit
  • Description
    Human BRCA 1/2 Gene Mutation Detection Kit. (High-Throughput sequencing) is used to detect BRCA-1 and BRCA-2 mutation that are responsible for avarian cancer and breast cancer, the detection of BRCA can guide the efficacity of platinum-based chemotherapy.
  • Specifications
    16tests/kit
  • Other Name
    Detection Kit for Human BRCA1 and BRCA2 Gene Mutation
  • Detection Process
    DNA/RNA extraction (RNA reverse transcription) + library construction (3,5 Hours)+ Sequencing+ One click data analysis
  • Samples Types
    Anticoagulant venous blood collection tube 10 ml Peripheral Blood, 7 section FFPE
  • Gene
    BRCA1, BRCA2
  • Reactivity
    Human
  • Advantages and Characteristics
    Easy operation: library construction can be done in two steps. Rapid Detection: Library construction takes only 3.5 hours, and it takes only 2 working days from sample extraction to report completing. Accurate and Reliable: The target fragment was amplified by specific primer, and this kit is applicable to paraffin tissue and peripheral blood samples. Comprehensive Inspection: As high-frequency mutation hot spots does not exist in the BRCA1 / 2 gene mutation, this kit achieves whole exome sequencing, to ensure the integrity of the detection.
  • Use
    CE-IVD
  • Additional description
    The detections of the targets with this kit is a type of test that can be performed on any target containing biological samples after clean up of interfering agents. The assay must be performed following the protocol. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Test
    Sequencing primers for deep sequencing kits  give sequencing nucleic acid results of DNA libraries, cDNAs. The MiSeq, HiSeq and NextSeq sequencing primers are designed to sequence the whole transcriptome.
  • Gene target
    BRCA   1/2   Gene   Mutation   Kit   Throughput  
  • Short name
    BRCA 1/2 Mutation Kit. ( -Throughput sequencing)
  • Technique
    sequencing, detection, sequencings
  • Species
    Human, Humans
  • Alternative name
    BRCA 1/2 Gene Mutation Detection Kit
  • Alternative technique
    sequencings, kits
  • Alternative to gene target
    v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832
  • Disease
    breast cancer, ovarian cancer
MeSH Data
  • Name
  • Concept
    Scope note: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
  • Tree numbers
    • E05.393.760.700
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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