ATG7 Recombinant Protein

• Catalog number
  95-122
• Price
  Please ask
• Size
  0.05 mg

• About recombinant protein
  Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1 (3). Another member of the autophagy family of proteins is APG7 which was identified in yeast as a ubiquitin-E1-like enzyme; this function is conserved in the mammalian homolog (4). In mammalian cells, APG7 is essential for autophagy conjugation systems, autophagosome formation, starvation-induced bulk degradation of proteins and organelles (5). It has been suggested that caspase-8 may alter APG7 levels and thus the APG7 program of autophagic cell death (6).
• Other name of the recombinant
  ATG7 Recombinant Protein: Agp7, Apg7l, Atg7l, Gm21553, 1810013K23Rik
• Recombinant in
  E. coli
• His tag on the recombinant protein
  Fusion Partner: C-terminal His-tag
• SEQUENCE
  aa 450 - 698
• Activity
  not available
• Use of recmbinant
  This recombinant protein can be used for WB, ELISA, MS and neutralization assays. For research use only.
• Protein is used in
  E, WB, MS
• Suspention medium
  1X PBS containing 10% glycerol
• Keep at
  Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  37589293
• Accession nr
  AAH58597
• KDa of reombinant
  30 kDa (Calculated)
• Pureity
  ~95%
• About
  Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
• Protein s origin
  Mouse
• Vial
  Liquid
• NCBI ID
  74244
• Gene name
  autophagy related 7
• Source
  Mus musculus
• Uniprot
  Q9D906
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  ATG7   Protein  
• Gene symbol
  Atg7
• Short name
  ATG7 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  ATG7 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:16935
• Gene
  ATG7
• Long gene name
  autophagy related 7
• Synonyms gene
  • APG7L
• Synonyms gene name
  • APG7 autophagy 7-like (S. cerevisiae)
  • ATG7 autophagy related 7 homolog (S. cerevisiae)
• Synonyms
  • GSA7
  • DKFZp434N0735
• Synonyms name
  • ubiquitin-activating enzyme E1-like protein
• GenBank acession
  • AF094516
• Locus
  3p25.3
• Discovery year
  2003-11-20
• Entrez gene record
  10533
• Pubmed identfication
  • 10233149
• RefSeq identity
  • NM_006395
• Classification
  • Ubiquitin like modifier activating enzymes
  • Autophagy related
• VEGA ID
  OTTHUMG00000129740

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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