CD47 Recombinant Antibody / IAP / Integrin Associated Protein

• Description:

  This antibody reacts with Ig domain of CD47/Integrin Associated Protein/IAP protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. It plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47/IAP may play a role in membrane transport and/or integrin dependent signal transduction.

• UniProt:

  Q08722

• Host:

  Mouse

• Immunogen:

  Recombinant full-length human protein was used as the immunogen for the recombinant Integrin Associated Protein antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 κ

• Type:

  Recombinant

• Applications:

  IHC-P

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Aliquot the recombinant Integrin Associated Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This recombinant Integrin Associated Protein antibody is available for research use only.

• CAS Number:

  9000-83-3