ACSS2-IN-2

• Description :

  ACSS2-IN-2 is an acyl-CoA synthetase short-chain family member 2 (ACSS2) inhibitor. ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several diseases, such as viral infection, metabolic disorders, neuropsychiatric diseases, inflammatory/autoimmune conditions and cancer[1].

• UNSPSC :

  12352005

• Target :

  Acetyl-CoA synthetase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/acss2-in-2.html

• Purity :

  99.49

• Solubility :

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(OC)C1=CC=CC(N2N=C(C)C(C(NC3=CC=CC(C(F)(F)C)=C3)=O)C2=O)=C1

• Molecular Formula :

  C21H19F2N3O4

• Molecular Weight :

  415.39

• References & Citations :

  [1]Philippe Nakache, et al. Acss2 inhibitors and methods of use thereof. Patent. WO2019097515A1.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2332820-04-7]