Anti-CD43 (T-Cell Marker) (rSPN/1094)
CAT:
37-BNUB1858-100
Size:
100 µL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-CD43 (T-Cell Marker) (rSPN/1094)
- Description: This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
- Synonyms: Galactoglycoprotein; GALGP; GPL115; Leukocyte sialoglycoprotein; Leukosialin; LSN; Sialophorin; SPN
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: SPN
- Gene ID: 6693
- NCBI Gene ID: 632188
- UniProt: P16150
- Cellular Locus: Plasma membrane
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant full-length human CD43 protein
- Target Antigen: CD43
- Clonality: Recombinant Monoclonal
- Isotype: IgG1 κ
- Clone: rSPN/1094
- Conjugation: Purified, with BSA
- Disease: Tumor
- Source: Animal
- Applications: Flow (verified) | IF (verified) | IHC, FFPE (verified) | WB (verified)
- Validated Applications: FC, IF, IHC, FFPE, WB
- Field of Research: Immunology
- Positive Control: K562 cells, Paracortex in a tonsil or a reactive lymph node.
- Concentration: 0.2 mg/mL
- Buffer: PBS, 0.05% BSA, 0.05% azide
- Molecular Weight: 95, 115, or 135 kDa
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years