Human CHMP2A Protein

Human CHMP2A Protein_x000D_ Catalog number: B2011941_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 µg_x000D_ Molecular Weight or Concentration: 1 mg/mL_x000D_ Supplied as: Solution_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20 °C_x000D_ Keywords: Putative breast adenocarcinoma marker BC2 protein, VPS2A protein, Vacuolar protein sorting associated protein 2 1., BC2 protein, CHMPA 2 protein, CHMP2A, putative breast adenocarcinoma marker protein, VPS2 protein, CHMPA 2, CHMPA-2 protein, BC-2 protein,_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Zhen Y, Spangenberg H, Munson MJ, Brech A, Schink KO, Tan KW, Sørensen V, Wenzel EM, Radulovic M, Engedal N, Simonsen A, Raiborg C, Stenmark H. ESCRT-mediated phagophore sealing during mitophagy Autophagy. 2020 May;16(5):826-841._x000D_ 2: Chen JJ, Nathaniel DL, Raghavan P, Nelson M, Tian R, Tse E, Hong JY, See SK, Mok SA, Hein MY, Southworth DR, Grinberg LT, Gestwicki JE, Leonetti MD, Kampmann M. Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation J Biol Chem. 2019 Dec 13;294(50):18952-18966._x000D_ 3: Hamdan FF, Srour M, Capo-Chichi JM, Daoud H, Nassif C, Patry L, Massicotte C, Ambalavanan A, Spiegelman D, Diallo O, Henrion E, Dionne-Laporte A, Fougerat A, Pshezhetsky AV, Venkateswaran S, Rouleau GA, Michaud JL. De novo mutations in moderate or severe intellectual disability PLoS Genet. 2014 Oct 30;10(10):e1004772._x000D_ 4: Bernareggi D, Xie Q, Prager BC, Yun J, Cruz LS, Pham TV, Kim W, Lee X, Coffey M, Zalfa C, Azmoon P, Zhu H, Tamayo P, Rich JN, Kaufman DS. CHMP2A regulates tumor sensitivity to natural killer cell-mediated cytotoxicity Nat Commun. 2022 Apr 7;13(1):1899._x000D_ 5: Alqabandi M, de Franceschi N, Maity S, Miguet N, Bally M, Roos WH, Weissenhorn W, Bassereau P, Mangenot S. The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization BMC Biol. 2021 Apr 8;19(1):66._x000D_ 6: Bertin A, de Franceschi N, de la Mora E, Maity S, Alqabandi M, Miguet N, di Cicco A, Roos WH, Mangenot S, Weissenhorn W, Bassereau P. Human ESCRT-III polymers assemble on positively curved membranes and induce helical membrane tube formation Nat Commun. 2020 May 29;11(1):2663._x000D_ 7: Hattori T, Takahashi Y, Chen L, Tang Z, Wills CA, Liang X, Wang HG. Targeting the ESCRT-III component CHMP2A for noncanonical Caspase-8 activation on autophagosomal membranes Cell Death Differ. 2021 Feb;28(2):657-670._x000D_ 8: Wang H, Wang Y, Wang X, Huang H, Bao J, Zhong W, Li A. PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure Cell Death Dis. 2021 Nov 16;12(12):1087._x000D_ 9: Takahashi Y, Liang X, Hattori T, Tang Z, He H, Chen H, Liu X, Abraham T, Imamura-Kawasawa Y, Buchkovich NJ, Young MM, Wang HG. VPS37A directs ESCRT recruitment for phagophore closure J Cell Biol. 2019 Oct 7;218(10):3336-3354._x000D_ 10: Sandrin V, Sundquist WI. ESCRT requirements for EIAV budding Retrovirology. 2013 Oct 9;10:104. _x000D_ _x000D_ Products Related to Human CHMP2A Protein can be found at Proteins

Catalog Number: B2011941 (100 µg)

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