SIRT2 (Sirtuin 2) Recombinant Human

• Description:

  SIRT2 (Sirtuin 2) Recombinant Human_x000D_ Catalog number: B2011240_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 ug_x000D_ Molecular Weight or Concentration: 35.5 kDa_x000D_ Supplied as: Solution_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20 °C_x000D_ Keywords: Recombinant Human SIRT2 Protein_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Lee YG, Reader BF, Herman D, Streicher A, Englert JA, Ziegler M, Chung S, Karpurapu M, Park GY, Christman JW, Ballinger MN. Sirtuin 2 enhances allergic asthmatic inflammation JCI Insight. 2019 Feb 21;4(4):e124710._x000D_ 2: Head PE, Zhang H, Bastien AJ, Koyen AE, Withers AE, Daddacha WB, Cheng X, Yu DS. Sirtuin 2 mutations in human cancers impair its function in genome maintenance J Biol Chem. 2017 Jun 16;292(24):9919-9931._x000D_ 3: Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan Nature. 2003 Sep 11;425(6954):191-6._x000D_ 4: Zhao D, Zou SW, Liu Y, Zhou X, Mo Y, Wang P, Xu YH, Dong B, Xiong Y, Lei QY, Guan KL. Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer Cancer Cell. 2013 Apr 15;23(4):464-76._x000D_ 5: Ding T, Hao J. Sirtuin 2 knockdown inhibits cell proliferation and RAS/ERK signaling, and promotes cell apoptosis and cell cycle arrest in multiple myeloma Mol Med Rep. 2021 Nov;24(5):760._x000D_ 6: Nguyen P, Shukla S, Liu R, Abbineni G, Smart DK. Sirt2 Regulates Radiation-Induced Injury Radiat Res. 2019 May;191(5):398-412._x000D_ 7: Suzuki T, Khan MN, Sawada H, Imai E, Itoh Y, Yamatsuta K, Tokuda N, Takeuchi J, Seko T, Nakagawa H, Miyata N. Design, synthesis, and biological activity of a novel series of human sirtuin-2-selective inhibitors J Med Chem. 2012 Jun 28;55(12):5760-73._x000D_ 8: Minten EV, Kapoor-Vazirani P, Li C, Zhang H, Balakrishnan K, Yu DS. SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation Cell Rep. 2021 Mar 30;34(13):108921._x000D_ 9: Walker MA, Chavez J, Villet O, Tang X, Keller A, Bruce JE, Tian R. Acetylation of muscle creatine kinase negatively impacts high-energy phosphotransfer in heart failure JCI Insight. 2021 Feb 8;6(3):e144301._x000D_ 10: Tervo AJ, Suuronen T, Kyrylenko S, Kuusisto E, Kiviranta PH, Salminen A, Leppänen J, Poso A. Discovering inhibitors of human sirtuin type 2: novel structural scaffolds J Med Chem. 2006 Nov 30;49(24):7239-41. _x000D_ _x000D_ Products Related to SIRT2 (Sirtuin 2) Recombinant Human can be found at Proteins

• Short Description:

  Catalog Number: B2011240 (100 ug) SIRT2 (Sirtuin 2) Recombinant Human

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3