RANTES/CCL5 (Human Recombinant)

• Description:

  Human RANTES/CCL5_x000D_ Catalog number: B2010369_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Human RANTES/CCL5 expressed in HEK 293. This protein acts as a potent CC chemokine, plays an important role in rheumatoid arthritis pathogenesis._x000D_ Storage: -20C_x000D_ Keywords: rHuRANTES/CCL5; C-C motif chemokine 5; SCYA5_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Agere SA, Akhtar N, Watson JM, Ahmed S. RANTES/CCL5 Induces Collagen_x000D_ Degradation by Activating MMP-1 and MMP-13 Expression in Human Rheumatoid_x000D_ Arthritis Synovial Fibroblasts. Front Immunol. 2017 Oct 18;8:1341._x000D_ _x000D_ 2: Nosalski R, Guzik TJ. Perivascular adipose tissue inflammation in vascular_x000D_ disease. Br J Pharmacol. 2017 Oct;174(20):3496-3513._x000D_ _x000D_ 3: Kim MO, Suh HS, Brosnan CF, Lee SC. Regulation of RANTES/CCL5 expression in_x000D_ human astrocytes by interleukin-1 and interferon-beta. J Neurochem. 2004_x000D_ Jul;90(2):297-308._x000D_ _x000D_ 4: Chatterton DE, Nguyen DN, Bering SB, Sangild PT. Anti-inflammatory mechanisms_x000D_ of bioactive milk proteins in the intestine of newborns. Int J Biochem Cell_x000D_ Biol. 2013 Aug;45(8):1730-47._x000D_ _x000D_ 5: Mustafa M, Wondimu B, Bakhiet M, Modéer T. Production of Rantes/CCL5 in human_x000D_ gingival fibroblasts challenged with tumor necrosis factor alpha. Eur J Oral_x000D_ Sci. 2001 Feb;109(1):44-9._x000D_ _x000D_ 6: Charni F, Friand V, Haddad O, Hlawaty H, Martin L, Vassy R, Oudar O, Gattegno_x000D_ L, Charnaux N, Sutton A. Syndecan-1 and syndecan-4 are involved in_x000D_ RANTES/CCL5-induced migration and invasion of human hepatoma cells. Biochim_x000D_ Biophys Acta. 2009 Oct;1790(10):1314-26._x000D_ _x000D_ 7: Suffee N, Richard B, Hlawaty H, Oudar O, Charnaux N, Sutton A. Angiogenic_x000D_ properties of the chemokine RANTES/CCL5. Biochem Soc Trans. 2011_x000D_ Dec;39(6):1649-53._x000D_ _x000D_ 8: Funk CJ, Wang J, Ito Y, Travanty EA, Voelker DR, Holmes KV, Mason RJ._x000D_ Infection of human alveolar macrophages by human coronavirus strain 229E. J Gen_x000D_ Virol. 2012 Mar;93(Pt 3):494-503._x000D_ 9: Skurk T, Mack I, Kempf K, Kolb H, Hauner H, Herder C. Expression and_x000D_ secretion of RANTES (CCL5) in human adipocytes in response to immunological_x000D_ stimuli and hypoxia. Horm Metab Res. 2009 Mar;41(3):183-9. _x000D_ _x000D_ Products Related to Human RANTES/CCL5 : Proteins

• Short Description:

  Catalog Number: B2010369 (10 ug)_x000D_ Human RANTES/CCL5 is a high quality research product used as highly pure Human RANTES/CCL5 expressed in HEK 293. This protein acts as a potent CC chemokine, plays an important role in rheumatoid arthritis pathogenesis. Custom bulk orders of this product are available upon request.

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3