Pinoresinol dimethyl ether

• UNSPSC Description:

  Pinoresinol dimethyl ether ((+)-Eudesmin) is a non-phenolic furofuran lignan isolated from Magnolia biondii with neuritogenic activity. Pinoresinol dimethyl ether ((+)-Eudesmin) can induce neuritis outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways[1][2].

• Target Antigen:

  PKA; PKC

• Type:

  Natural Products

• Related Pathways:

  Epigenetics;Stem Cell/Wnt;TGF-beta/Smad

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/pinoresinol-dimethyl-ether.html

• Purity:

  99.39

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  COC1=CC=C([C@H]2OC[C@]3([H])[C@@H](C4=CC=C(OC)C(OC)=C4)OC[C@@]32[H])C=C1OC

• Molecular Weight:

  386.44

• References & Citations:

  [1]TeruhisaMiyauchi, et al. Formation of (+)-eudesmin in Magnolia kobus DC. Var. borealis sarg. Phytochemistry, 1998, 47(4): 665-670.|[2]Yang YJ, et al. Effects of (+)-eudesmin from the stem bark of magnolia kobus DC. var. borealis Sarg. on neurite outgrowth in PC12 cells. Arch Pharm Res. 2006 Dec;29(12):1114-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  29106-36-3