β,β-Dimethylacrylshikonin

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T3S2344-5mg	β,β-Dimethylacrylshikonin
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CAT:

804-HY-N5112B-02

Size:

10 mg

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β,β-Dimethylacrylshikonin

CAS Number: 24502-79-2
UNSPSC Description: β,β-Dimethylacrylshikonin (Isoarnebin I) is a naphthoquinone derivative isolated from Lithospermum erythrorhizon Sieb. et Zucc. , promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway.β,β-Dimethylacrylshikonin has anti-tumor activity[1].
Target Antigen: HIF/HIF Prolyl-Hydroxylase
Type: Natural Products
Related Pathways: Metabolic Enzyme/Protease
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/beta-beta-dimethylacrylshikonin.html
Purity: 99.30
Solubility: DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles: O=C1C2=C(O)C=CC(O)=C2C(C=C1[C@@H](C/C=C(C)/C)OC(/C=C(C)/C)=O)=O
Molecular Weight: 370.40
References & Citations: [1]Zeng Z, et al. Arnebin-1 promotes angiogenesis by inducing eNOS, VEGF and HIF-1α expression through the PI3K-dependent pathway. Int J Mol Med. 2015 Sep;36(3):685-97.|[2]Sidhu GS, et al. Arnebin-1 accelerates normal and hydrocortisone-induced impaired wound healing. J Invest Dermatol. 1999 Nov;113(5):773-81.
Shipping Conditions: Room Temperature
Storage Conditions: 4°C (Powder, protect from light)
Clinical Information: No Development Reported

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HY-N5112B-03	β,β-Dimethylacrylshikonin
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