Purpurin 18

• UNSPSC Description:

  Purpurin 18, a derivative of chlorophyll and a type of dihydroporphyrin, is used to produce photosensitizers. Purpurin 18 photodynamic therapy can induce cell apoptosis and has anti-tumor activity[1][2].

• Target Antigen:

  Apoptosis; Reactive Oxygen Species

• Type:

  Reference compound

• Related Pathways:

  Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/purpurin-18.html

• Purity:

  95.0

• Solubility:

  DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)|Ethanol : < 1 mg/mL

• Smiles:

  O=C(O1)/C2=C([C@H]3CCC(O)=O)/N=C([C@H]3C)/C=C(C(C)=C/4C=C)\NC4=C/C5=N/C(C(CC)=C5C)=C\C6=C(C)C(C1=O)=C2N6

• Molecular Weight:

  564.63

• References & Citations:

  [1]NicolasDrogat, et al. High yield preparation of purpurin-18 from Spirulina maxima. Dyes and Pigments|[2]Pengyun Huang, et al. Photodynamic treatment with purpurin 18 effectively inhibits triple negative breast cancer by inducing cell apoptosis. Lasers Med Sci. 2021 Mar;36(2):339-347.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  25465-77-4