ML 315 (hydrochloride)
CAT:
804-HY-117608A-01
Size:
50 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ML 315 (hydrochloride)
- Product Name Alternative: Desmethyldoxepin (hydrochloride)
- CAS Number: 2172559-91-8
- UNSPSC Description: ML 315 is a selective dual inhibitor of CDK and DYRK with IC50s of 68 nM and 282 nM, respectively. ML 315 is used in cancer and neurological disease research[1].
- Target Antigen: CDK; DYRK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage;Protein Tyrosine Kinase/RTK
- Field of Research: Cancer; Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/ml-315-hydrochloride.html
- Purity: 98.75
- Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: [H]Cl.ClC1=CC(CNC2=NC=NC=C2C3=CC=C4OCOC4=C3)=CC(Cl)=C1
- Molecular Weight: 410.68
- References & Citations: [1]Coombs TC, et al. Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3654-61.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: No Development Reported