Recombinant Varicella-zoster virus Tegument protein UL47 homolog (ORF11) , partial

Recombinant Varicella-zoster virus Tegument protein UL47 homolog (ORF11) , partial

• CAS Number: 9000-83-3
• Gene Name: ORF11
• UniProt: P09263
• Expression Region: 354-808aa
• Organism: Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3)
• Target Sequence: IERILVEDVFLDRRASSKTHKYGPRWNSVYALPYNAGKMYVQHIPGFYDVSLRAVGQGTAIWHHMILSTAACAISNRISHGDGLGFLLDAAIRISANCIFLGRNDNFGVGDPCWLEDHLAGLPREAVPDVLQVTQLVLPNRGPTVAIMRGFFGALAYWPELRIAISEPSTSLVRYATGHMELAEWFLFSRTHSLKPQFTPTEREMLASFFTLYVTLGGGMLNWICRATAMYLAAPYHSRSAYIAVCESLPYYYIPVNSDLLCDLEVLLLGEVDLPTVCESYATIAHELTGYEAVRTAATNFMIEFADCYKESETDLMVSAYLGAVLLLQRVLGHANLLLLLLSGAALYGGCSIYIPRGILDAYNTLMLAASPLYAHQTLTSFWKDRDDAMQTLGIRPTTDVLPKEQDRIVQASPIEMNFRFVGLETIYPREQPIPSVDLAENLMQYRNEILGLDW
• Tag: N-terminal 10xHis-tagged and C-terminal Myc-tagged
• Source: E.coli
• Field of Research: Others
• Assay Type: In Stock Protein
• Relevance: Tegument protein that can bind to various RNA transcripts. Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase ORF17/VHS. Plays also a role in the primary envelopement of virions in the perinuclear space, probably by interacting with two nuclear egress proteins ORF24 and ORF27.
• Purity: Greater than 85% as determined by SDS-PAGE.
• Activity: Not Test
• Length: Partial
• Form: Liquid or Lyophilized powder
• Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Molecular Weight: 58.3 kDa
• References & Citations: "Identification and functional characterization of the Varicella zoster virus ORF11 gene product." Che X., Oliver S.L., Sommer M.H., Rajamani J., Reichelt M., Arvin A.M. Virology 412:156-166 (2011)
• Storage Conditions: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.