Nitroprusside (disodium dihydrate)

• UNSPSC Description:

  Nitroprusside disodium dehydrate (Sodium nitroprusside dihydrate) is a vasodilator that available for the research of acute hypertension, heart failure. Nitroprusside disodium dehydrate induces autophagy in glutathione-depleted osteoblasts. Nitroprusside disodium dehydrate acts as a nitric oxide (NO) donor in a rat intestinal ischemia reperfusion model[1][2][3][4].

• Target Antigen:

  Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cardiovascular Disease; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Nitroprusside-disodium-dihydrate.html

• Purity:

  99.72

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)

• Smiles:

  [Na2[Fe(CN)5NO].2H2O]

• Molecular Weight:

  297.95

• References & Citations:

  [1]Namazi, H., Sodium nitroprusside as a nitric oxide donor in a rat intestinal ischemia reperfusion model: a novel molecular mechanism. Clinics (Sao Paulo), 2008. 63(3): p. 405.|[2]J N Cohn, et al. Nitroprusside. Ann Intern Med. 1979 Nov;91(5):752-7.|[3]Min Jeong Son, et al. Sodium nitroprusside induces autophagic cell death in glutathione-depleted osteoblasts. J Biochem Mol Toxicol. Sep-Oct 2010;24(5):313-22.|[4]Liuqin Yang, et al. Sodium nitroprusside (SNP) sensitizes human gastric cancer cells to TRAIL-induced apoptosis. Int Immunopharmacol. 2013 Oct;17(2):383-9.Chem Eng J. 15 August 2022, 136169.|Exp Eye Res. 2024 Apr 5:243:109886.|Biochim Biophys Acta Mol Basis Dis. 2024 Jul 25:167437.|Br J Pharmacol. 2021 Aug 6.|J Ethnopharmacol. 2024 Aug 23:118727.|J Neuroinflammation. 2023 Feb 24;20(1):49.|Neuroscience. 2024 Oct 24:S0306-4522(24)00549-9.|Redox Biol. 2023 Dec 18:69:103004.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  Launched

• CAS Number:

  13755-38-9