QWF Peptide

QWF Peptide

• CAS Number: 126088-82-2
• UNSPSC Description: QWF Peptide (Compound 4a) is a substance P antagonist with an IC50 of 0.09 μM. QWF Peptide antagonizes the SP-induced contraction of isolated guinea pig trachea strips with an IC50 of 4.7 μM[1].
• Target Antigen: Neurokinin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/qwf-peptide.html
• Smiles: O=C(OCC1=CC=CC=C1)[C@H](CC2=CC=CC=C2)NC([C@@H](CC3=CN(C=O)C4=C3C=CC=C4)NC([C@H](CCC(N)=O)NC(OC(C)(C)C)=O)=O)=O
• Molecular Weight: 697.78
• References & Citations: [1]Hagiwara D, et al. Studies on neurokinin antagonists. 1. The design of novel tripeptides possessing the glutaminyl-D-tryptophylphenylalanine sequence as substance P antagonists. J Med Chem. 1992 May 29;35(11):2015-25.
• Shipping Conditions: Blue Ice