Fluorogenic Caspase (Apopain) Substrate 1f-z

• Description:

  Fluorogenic Caspase (Apopain) Substrate 1f-z_x000D_ Catalog number: B2011408_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 5 mg_x000D_ Molecular Weight or Concentration: 821.7 g/mol_x000D_ Supplied as: Lyophilized_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20 °C_x000D_ Keywords: Caspase 3 (Apopain) Substrate 1f-z, fluorogenic_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Xiong C, Lu W, Zhang R, Tian M, Tong W, Gelovani J, Li C. Cell-permeable [99mTc(CO3)]-labeled fluorogenic caspase 3 substrate for dual-modality detection of apoptosis Chemistry. 2009 Sep 14;15(36):8979-84._x000D_ 2: Mackay M, Pérez-López AM, Bradley M, Lilienkampf A. Eliminating caspase-7 and cathepsin B cross-reactivity on fluorogenic caspase-3 substrates Mol Biosyst. 2016 Mar;12(3):693-6._x000D_ 3: Pérez-López AM, Soria-Gila ML, Marsden ER, Lilienkampf A, Bradley M. Fluorogenic Substrates for In Situ Monitoring of Caspase-3 Activity in Live Cells PLoS One. 2016 May 11;11(5):e0153209._x000D_ 4: Lee BW, Johnson GL, Hed SA, Darzynkiewicz Z, Talhouk JW, Mehrotra S. DEVDase detection in intact apoptotic cells using the cell permeant fluorogenic substrate, (z-DEVD)2-cresyl violet Biotechniques. 2003 Nov;35(5):1080-5._x000D_ 5: Kitevska T, Roberts SJ, Pantaki-Eimany D, Boyd SE, Scott FL, Hawkins CJ. Analysis of the minimal specificity of caspase-2 and identification of Ac-VDTTD-AFC as a caspase-2-selective peptide substrate Biosci Rep. 2014 Apr 1;34(2):e00100._x000D_ 6: Poreba M, Rut W, Groborz K, Snipas SJ, Salvesen GS, Drag M. Potent and selective caspase-2 inhibitor prevents MDM-2 cleavage in reversine-treated colon cancer cells Cell Death Differ. 2019 Dec;26(12):2695-2709._x000D_ 7: He L, Ye S, Fang J, Zhang Y, Cui C, Wang A, Zhao Y, Shi H. Real-Time Visualization of Embryonic Apoptosis Using a Near-Infrared Fluorogenic Probe for Embryo Development Evaluation Anal Chem. 2021 Sep 7;93(35):12122-12130._x000D_ 8: Castro MM, Fuah J, Ali M, Sung M, Schulz J, Kondo MY, Fan X, Holt A, Schulz R. Inhibitory effects of caspase inhibitors on the activity of matrix metalloproteinase-2 Biochem Pharmacol. 2013 Aug 15;86(4):469-75._x000D_ 9: Fuente-Garcia C, Sentandreu E, Aldai N, Sentandreu MA. Optimization of a fluorogenic assay to determine caspase 3/7 activity in meat extracts Food Sci Technol Int. 2022 Mar;28(2):128-134._x000D_ 10: Peterson QP, Goode DR, West DC, Botham RC, Hergenrother PJ. Preparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesis Nat Protoc. 2010 Feb;5(2):294-302. _x000D_ _x000D_ Products Related to Fluorogenic Caspase (Apopain) Substrate 1f-z can be found at Substrates

• Short Description:

  Catalog Number: B2011408 (5 mg)_x000D_ Fluorogenic Caspase (Apopain) Substrate 1f-z is a high quality AFC (7-amino-4-trifluoromethylcoumarin)-derived caspase substrate used for the fluorimetric detection of caspase activities. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5