Anti-BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma)(BARX1/2759), CF405S conjugate
CAT:
37-BNC042759-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma)(BARX1/2759), CF405S conjugate
- Description: BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes hepatocellular carcinoma cell (HCC) migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: BARX1; Homeobox protein BarH-like 1; BARX homeobox 1
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: BARX1
- Gene ID: 56033
- NCBI Gene ID: 164960
- UniProt: Q9HU1
- Cellular Locus: Nucleus
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant fragment of human BARX1 protein (around aa 155-254) (exact sequence is proprietary)
- Target Antigen: BARX1
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: BARX1/2759
- Conjugation: CF405S
- Disease: Tumor
- Source: Animal
- Applications: IHC, FFPE (verified)
- Validated Applications: IHC, FFPE
- Field of Research: Transcription factor
- Positive Control: HepG2 cell lysate. Pancreas.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 24 kDa
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years