GT 949

GT 949

• CAS Number: 460330-27-2
• UNSPSC Description: GT 949 is a selective excitatory amino acid transporter-2 (EAAT2) positive allosteric modulator with an EC50 of 0.26 nM[1].
• Target Antigen: EAAT
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/GT_949.html
• Purity: 99.25
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: O=C1NC2=C(C=C(OC)C=C2)C=C1C(N3CCN(C4CCCCC4)CC3)C5=NN=NN5CCC6=CC=CC=C6
• Molecular Weight: 527.66
• References & Citations: [1]Kortagere S, et al. Identification of Novel Allosteric Modulators of Glutamate Transporter EAAT2. ACS Chem Neurosci. 2018 Mar 21;9(3):522-534.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported