AF488 Anti-Mouse CD3ε Antibody

• Background:

  CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

• Synonyms:

  T-cell surface glycoprotein CD3 epsilon chain, CD3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E

• Gene ID:

  12501

• Swiss Prot:

  P22646

• Host:

  Armenian Hamster

• Reactivity:

  Mouse

• Isotype:

  IgG

• Conjugation:

  AF488

• Applications:

  FCM

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• CAS Number:

  9007-83-4