Mouse IL-38 Protein, His tag (Animal-Free)

• Description:

  Interleukin 38 (IL-38) is a 16.87 kDa cytokine with 152 amino acid residues and a member of the interleukin-1 (IL-1) family. IL-38 is primarily secreted from basal epithelia of the skin and B cells of the tonsil, spleen, and thymus. It plays essential roles in inflammation and host defense by mediating NF-κB, AP1, and JNK signaling pathways when IL-38 binds to the receptors like IL1RAPL1 and IL-36R. In addition, IL-38 participates in down-regulating cell proliferation, migration, and up-regulating IL-6 and IL-10.

• Type:

  Cytokines and proteins

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Please store the whole kit at -20°C upon receipt ,and protect from light. The kit is valid for 17 months. Please refer to the table below Materials supplied and Storage conditions to store all the components.