Inhibin alpha Antibody / INHA antibody

• Description:

  It recognizes a 47kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH) . Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.

• Specifications:

  Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

• UniProt:

  P05111

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 73-96 from the huma protein was used as the immunogen for the Inhibin alpha antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG2a

• Clone:

  INHA/4266

• Applications:

  IHC-P

• Purity:

  Protein G affinity chromatography

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Store the Inhibin alpha antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

• Limitations:

  This Inhibin alpha antibody is available for research use only.

• Storage Conditions:

  Store the Inhibin alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

• Formulation:

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes:

  Optimal dilution of the Inhibin alpha antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Nuclear and Cytoplasmic (secreted)

• Image Legend:

  IHC staining of FFPE human testis with Inhibin alpha antibody (clone INHA/4266) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.