Integrin beta 3 Recombinant Antibody / ITGB3 / CD61
CAT:
800-V8413-100UG
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Integrin beta 3 Recombinant Antibody / ITGB3 / CD61
- Description: Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61). The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
- CAS Number: 9000-83-3
- UniProt: P05106
- Host: Mouse
- Immunogen: Recombinant full-length human CD61 protein was used as the immunogen for the recombinant CD61 antibody.
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Type: Recombinant
- Applications: IHC-P
- Format: Purified
- Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
- Reconstitution: Store the recombinant CD61 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
- Limitations: This recombinant CD61 antibody is available for research use only.