CD79a Recombinant Antibody

CD79a Recombinant Antibody

• Description: The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR). CD79a plays multiple and diverse roles in B cell development and function. The CD79a/b heterodimer associates non-covalently with the immunoglobulin heavy chain through its transmembrane region, thus forming the BCR along with the immunoglobulin light chain and the pre-BCR when associated with the surrogate light chain in developing B cells. Association of the CD79a/b heterodimer with the immunoglobulin heavy chain is required for surface expression of the BCR and BCR induced calcium flux and protein tyrosine phosphorylation. [Wiki]
• CAS Number: 9000-83-3
• UniProt: P11912
• Host: Rabbit
• Immunogen: Amino acids 202-216 (GTYQDVGSLNIADVQ) were used as the immunogen for the recombinant CD79a antibody.
• Clonality: Monoclonal
• Isotype: IgG κ
• Type: Recombinant
• Applications: IHC-P, WB, FACS, IF
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Reconstitution: Store the recombinant CD79a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This recombinant CD79a antibody is available for research use only.