Acetyl-Histone H2A Antibody (Lys9)

• Description:

  Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [UniProt]

• Specifications:

  Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:500-1:1000

• UniProt:

  P04908

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  A synthetic peptide specific to human Histone H2A (surrounding acetylated lysine 9) was used as the immunogen for the Histone H2A antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Clone:

  DEB-8

• Type:

  Recombinant

• Applications:

  IHC-P, WB

• Purity:

  Affinity purified

• Format:

  Purified

• Buffer:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

• Reconstitution:

  Store the acetyl-Histone H2A Antibody (Lys9) at -20oC.

• Limitations:

  This acetyl-Histone H2A Antibody (Lys9) is available for research use only.

• Storage Conditions:

  Store the acetyl-Histone H2A Antibody (Lys9) at -20°C.

• Formulation:

  Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

• Applications Notes:

  Optimal dilution of the acetyl-Histone H2A Antibody (Lys9) should be determined by the researcher.

• CAS Number:

  9000-83-3

• Location:

  Nuclear

• Image Legend:

  Western blot testing of lysate from human HeLa cells treated with Trichostatin A, with acetyl-Histone H2A Antibody (Lys9) . Predicted molecular weight ~14 kDa.