NEDD9 Antibody

• Description:

  Neural cell expressed developmentally down regulated 9, also called Enhancer of filamentation 1 (EF1), is a protein that in humans is encoded by the NEDD9 gene. The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. NEDD9 is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. It has also been reported to have a role in cancer metastasis. NEDD9 is a highly relevant cancer gene that governs metastatic potential in human melanoma. Additionally, it has been speculated that it may be an important linking element between extracellular signaling and regulation of the cytoskeleton.

• Host:

  Rabbit

• Immunogen:

  Human partial recombinant protein (AA 273-E21) was used as the immunogen for this NEDD9 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB

• Format:

  Antigen affinity purified

• Buffer:

  0.5mg/ml if reconstituted with 0.2ml sterile DI water

• Reconstitution:

  After reconstitution, the NEDD9 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This HEF1 antibody is available for research use only.

• CAS Number:

  9007-83-4