CPM Antibody / Carboxypeptidase M

• Description:

  The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq].

• Specifications:

  Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

• UniProt:

  P14384

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 212-241 from the human protein was used as the immunogen for the CPM antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, IHC-P

• Purity:

  Antigen affinity purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the CPM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This CPM antibody is available for research use only.

• Storage Conditions:

  Aliquot the CPM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  The stated application concentrations are suggested starting points. Titration of the CPM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of human kidney tissue lysate with CPM antibody. Expected molecular weight: 51-65 kDa depending on glycosylation level.