HSP90 Antibody / HSP90AA1

• Description:

  Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

• Specifications:

  Western blot: 1:1000

• UniProt:

  P07900

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This HSP90 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 299-331 amino acids from the Central region of human HSP90AA1.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS pH 7.4 with 0.09% sodium azide

• Reconstitution:

  Aliquot the HSP90 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This HSP90 antibody is available for research use only.

• Storage Conditions:

  Aliquot the HSP90 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the HSP90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Bovine, Chicken, Hamster, Pig, Rabbit, Rat, Zebrafish

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot analysis of lysate from A431, A549, HeLa, SK-N-MC, mouse NIH3T3 cell line using HSP90 antibody diluted at 1:1000 for each lane.