Complement C5 Antibody

Complement C5 Antibody

• Description: C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
• CAS Number: 9007-83-4
• UniProt: P01031
• Host: Rabbit
• Immunogen: A portion of amino acids 253-281 from the human protein was used as the immunogen for this C5 antibody.
• Clonality: Polyclonal
• Isotype: Ig
• Applications: IHC, FACS, WB, ELISA
• Format: Antigen affinity purified
• Buffer: In 1X PBS, pH 7.4, with 0.09% sodium azide
• Reconstitution: Aliquot the C5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This C5 antibody is available for research use only.