SRC Antibody (Y419) [APR06101G]

• Background:

  Tissue Location: Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues

• Synonyms:

  Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src, SRC, SRC1

• Gene Name:

  HGNC:11283

• Gene ID:

  6714

• UniProt:

  P12931

• Chromosomal Location:

  Cell membrane; Lipid-anchor. Mitochondrion inner membrane. Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell junction, focal adhesion. Note=Localizes to focal adhesion sites following integrin engagement (PubMed:22801373) . Localization to focal adhesion sites requires myristoylation and the SH3 domain (PubMed:7525268) . Colocalizes with PDLIM4 at the perinuclear region, but not at focal adhesions (PubMed:19307596)

• Applications:

  WB, IHC-P, IF

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  214116251138973018586953785350787555291458596312615910161861082010083521309750194199661458596322710723205256941930759625731159

• Molecular Weight:

  59835

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SRC Antibody (Y419) [APR06101G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=6714

• Uniprot URL:

  https://www.uniprot.org/uniprot/P12931