DLG7 Antibody (N-term) [APR05078G]

• Background:

  Tissue Location: Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta

• Synonyms:

  Disks large-associated protein 5, DAP-5, Discs large homolog 7, Disks large-associated protein DLG7, Hepatoma up-regulated protein, HURP, DLGAP5, DLG7, KIAA0008

• Gene Name:

  DLGAP5

• Gene ID:

  9787

• UniProt:

  Q15398

• Chromosomal Location:

  Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.

• Molecular Weight:

  95115

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DLG7 Antibody (N-term) [APR05078G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=9787

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15398