SFRS7 Antibody (N-term) [APR13286G]

• Background:

  Tissue Location: Brain, liver, kidney and lung.

• Synonyms:

  Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7, SFRS7

• Gene Name:

  SRSF7

• Gene ID:

  6432

• UniProt:

  Q16629

• Chromosomal Location:

  Nucleus. Cytoplasm

• Applications:

  WB, IHC-P

• Dilution:

  WB--1:1000 IHC-P--1:100~500

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1- NXT1 heterodimer for export (TAP/NXF1 pathway) ; enhances NXF1-NXT1 RNA- binding activity. RNA-binding is semi-sequence specific.

• Molecular Weight:

  27367

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SFRS7 Antibody (N-term) [APR13286G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=6432

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q16629