ML 190

CAT:

804-HY-107749-02

Size:

10 mg

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CAS Number: 1355244-02-8
UNSPSC Description: ML 190 is a selective κ opioid receptor (KOR) antagonist with an IC50 of 120 nM and an EC50 of 129 nM, respectively[1].
Target Antigen: Opioid Receptor
Type: Reference compound
Related Pathways: GPCR/G Protein;Neuronal Signaling
Applications: Neuroscience-Neuromodulation
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/ml-190.html
Purity: 98.2
Solubility: DMSO : 9.77 mg/mL (ultrasonic;warming)
Smiles: O=C1C2=CC=CN2C3=C(C)C=CN=C3N1CC(NCCCN4CCN(CC4)C5=CC=C(C=C5)OC)=O
Molecular Weight: 488.58
References & Citations: [1]Frankowski KJ, et al. Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy. ACS Chem Neurosci. 2012;3(3):221-236.
Shipping Conditions: Room Temperature
Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information: No Development Reported

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